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In Brief

Rio athletes gut health
Team GB athletes suffer gut trouble in Rio. Olympic stomach upsets ‘could be leaky gut’
Plymouth University read more

Run247 news article
Colostrum science review
www.run247.com read more

neovite - the riders video
Our successful athletes describe their results
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Prof Ray Playford, gastroenterologist,
Queen Mary's College, a video interview
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Performance in Trained Cyclists
The Influence of Bovine Colostrum Supplementation on Exercise   -- Shing et al.,
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Triathletes Report
An anecdotal study of twelve ailing readers of 220TRIATHLON magazine who report on their use of neovite (13 pages pdf)
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Cycling Competition Report
After an appeal in Cycling Weekly, a group of eighteen volunteers report on using neovite for overtraining fatigue and health problems (46 pages pdf)
neovite read more

Lactoferrin could help osteoporosis
Taking a drink rich in lactoferrin may help to prevent osteoporosis as it has powerful bone-building properties.
Endocrinology read more

'Sporting benefits of mothers milk'
Colostrum is reviewed as a hot supplement for sports and intestinal health...
The Times read more

Multi-functional food for Health & Performance

neovite is a milk powder from milk collected in the first hours after calving. It is an exceptional natural food prized by many cultures for thousands of years


Digestive efficiency

This information is not generally allowed to viewed online as the public description of the health benefits of foodstuffs is restricted under EU regulations 1924/2006.

Published science in peer-reviewed journals may be permitted, so here is the abstract from our published research

The American Journal of Physiology - Gastro-intestinal and Liver Physiology
Published online before print December 2010, in print March 2011 vol. 300 no. 3 G477-G484

"bovine colostrum truncates the increase in gut permeability caused by heavy exercise in athletes"

1. Tania Marchbank (1), 2. Glen Davison (2), 3. Jemma R. Oakes (2), 4. Mohammad A. Ghateib (3), 5. Michael Patterson (3), 6. Mary Pat Moyer (4), 7. Raymond J. Playford (1)

+ Author Affiliations

(1) Digestive Diseases, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine, Queen Mary University of London, London;

(2) Department of Sport and Exercise Science, Aberystwyth University, Aberystwyth;

(3) Department of Metabolic Medicine, Hammersmith Hospital, Imperial College London, London, United Kingdom;

(4) INCELL Corporation, San Antonio, Texas

Heavy exercise causes gut symptoms and, in extreme cases, “heat stroke” partially due to increased intestinal permeability of luminal toxins.

We examined bovine colostrum, a natural source of growth factors, as a potential moderator of such effects. Twelve volunteers completed a double-blind, placebo-controlled, crossover protocol (14 days colostrum/placebo) prior to standardized exercise. Gut permeability utilized 5 h urinary lactulose-to-rhamnose ratios.

In vitro studies (T84, HT29, NCM460 human colon cell lines) examined colostrum effects on temperature-induced apoptosis (active caspase-3 and 9, Baxá, Bcl-2), heat shock protein 70 (HSP70) expression and epithelial electrical resistance.

In both study arms, exercise increased blood lactate, heart rate, core temperature (mean 1.4°C rise) by similar amounts.

Gut hormone profiles were similar in both arms although GLP-1 levels rose following exercise in the placebo but not the colostrum arm (P = 0.026). Intestinal permeability in the placebo arm increased 2.5-fold following exercise (0.38 ± 0.012 baseline, to 0.92 ± 0.014, P < 0.01), whereas colostrum truncated rise by 80% (0.38 ± 0.012 baseline to 0.49 ± 0.017) following exercise.

In vitro apoptosis increased by 47–65% in response to increasing temperature by 2°C. This effect was truncated by 60% if colostrum was present (all P < 0.01).

Similar results were obtained examining epithelial resistance (colostrum truncated temperature-induced fall in resistance by 64%, P < 0.01).

Colostrum increased HSP70 expression at both 37 and 39°C (P < 0.001) and was truncated by addition of an EGF receptor-neutralizing antibody. Temperature-induced increase in Baxá and reduction in Bcl-2 was partially reversed by presence of colostrum.

Colostrum may have value in enhancing athletic performance and preventing heat stroke